Will my graphics card work in all PCIe slots?

PCIe release tab broken! gpu blocking pcie slot Poor component placement impacting GPU is somewhat common On a lot of ROG boards, putting anything in the last PCIe slot or even next to last slot will block a gpu slot size PCI EXPRESS slot 1: NVIDIA 1080TI PCI EXPRESS slot 2: none Cant use the last PCI express port as my radiator fan is blocking the slot

gpu with m2 slot The PCIe slots on motherboards can be a bit confusing It would be SIMPLE if they were all full